Thiamin is a water-soluble vitamin (Vitamin B1) that is not stored in appreciable amounts; thus, it must be constantly supplied in the daily diet or through supplementation. The highest concentrations of Vitamin B1 are found in muscle, heart, liver, kidneys and the brain. In food, thiamin can be found in free form as thiamine pyrophosphate (TPP) and as a protein phosphate complex.
Functions of Vitamin B1:
• As a coenzyme, B1 plays a key role in energy production
• Precursor of thiamin pyrophosphate (TPP) or co-carboxylase, a coenzyme required by dehydrogenase in the citric acid cycle (Krebs’ cycle) and by transketolase in the pentose phosphate shunt
• Affects all tissue especially nerve membranes, nerve conduction, the stomach and heart
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